Relic
Vanguard's Memento
Rare
Effect
At start of combat, inflict 45 Burn on all enemies per 
Vanguard in combat.
Where it drops
- The Curse of the Kiss - “Gain Vanguard's Memento. All Heroes permanently lose 1 {stat}.”
- The Debtor - “Debt II (15 Shards)”
- The Etched Path - “Relic path (higher tier)”
- The Three Urns - “Relic urn”
- The Void Beast - “Gain Vanguard's Memento. Your Heroes start next combat Stunned for 6 seconds.”
- The Well of Temptations - “Rare relic outcome”
- Trial: Rematch - “Victory reward”
- Choose a Rare Relic - “Gain {relic}.”
Other Rare relics
Questions people ask
What does Vanguard's Memento do in Guildrun?
At start of combat, inflict 45 Burn on all enemies per Vanguard in combat.
What is the difference between a relic and an item?
Items are equipped by a single hero and take up one of that hero's slots. Relics apply to the entire guild and do not use slots. That makes relics the stronger of the two when a build starts coming together.
How do I increase my team size?
Harmony Crystal raises it by one, up to five. So does each of the fifteen Mandate relics, but those require finishing an objective first, like dealing 15000 auto attack damage or applying 30000 shields. Pick the Mandate that matches what your team already does.